Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina

Bella, Santiago Rafael, Llugdar, José Roberto, Biagi Bistoni, Marta Inés, Pellicioni, Patricia, Lerda, Daniel Enrique ORCID: https://orcid.org/0000-0002-1257-0954, Labrador, Jorge, Fernández Cruz, G. and Martins, C. (2015) Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina. ARC Journal of Cancer Science (AJCS), 1 (1). pp. 11-16. ISSN 2455-6009

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Resumen

The discovery of BRCA1 and BRCA2 genes has led to the introduction of increasingly sophisticated genetic tests to measure the risk of hereditary breast cancer, among other things. The aim of this study was to determine the prevalence of the mutation in 24 women from Córdoba with breast / ovarian cancer (BC / OC) and with at least two relatives with breast cancer. Although there are recurrent mutations, which appear repeatedly in unrelated families, with highest prevalence as in the Jewish ethnicity, this is the first study on the population of the province of Córdoba, Argentina.

Tipo de documento:	Artículo
Palabras clave:	Cáncer hereditario. Cáncer de mama. Cáncer de ovario. Mutaciones.
Temas:	R Medicina > R Medicina (General) R Medicina > RC Medicina interna > RC0254 Neoplasias. Los tumores. Oncología (incluyendo cáncer)
Unidad académica:	Universidad Católica de Córdoba > Facultad de Ciencias de la Salud
Google Académico:	Ver citaciones
URI:	http://pa.bibdigital.ucc.edu.ar/id/eprint/1466

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