Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]

Bertorello, Natalia Belén dir. ORCID: https://orcid.org/0000-0002-6768-0122, Eynard, Aldo R. ORCID: https://orcid.org/0000-0002-0366-3112 and Defagó, María Daniela ORCID: https://orcid.org/0000-0002-8878-3067 (2022) Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]. Revista Chilena de Nutricion, 49 (1). pp. 133-146. ISSN 0717-7518

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Resumen

Metabolic syndrome (MS) is a global health problem. Dietary factors, especially fatty acids, may affect MS pathology. However, the associations between omega-3 polyunsaturated fatty acids (n-3 PUFAs) and MS risk demonstrate inconsistent results. To clarify the relationship between dietary n-3 PUFA and endothelial function on MS, we carried out a systematic review. An electronic literature search based on controlled clinical trials (CCTs) between 2004 and 2020 was conducted. A total of 28 articles were included in the systematic review. Studies were analyzed according intervention type: dietary interventions (12 CCTs), dietary supplementation interventions (9 CCTs) and mixed interventions (7 CCTs). Studies with dietary interventions characterized by n-3 PUFAs increased by food source, such as Mediterranean and Nordic-style diets, reported significant reduction in systolic and diastolic blood pressure, and also in inflammatory endothelial biomarkers. The same effect was also observed in mixed interventions and in CCTs with n-3 PUFAs supple-mentation. Dietary interventions with n-3 PUFAs contributes to improved endothelial and cardiovascular health in SM and associated risk factors.

Tipo de documento:	Artículo
DOI:	https://doi.org/10.4067/S0717-7518202200010013
Palabras clave:	Ensayos clínicos controlados. Función endotelial. Síndrome metabólico.
Temas:	Q Ciencia > Q Ciencia (General) R Medicina > R Medicina (General)
Unidad académica:	Universidad Católica de Córdoba > Facultad de Ciencias de la Salud
Google Académico:	Ver citaciones
URI:	http://pa.bibdigital.ucc.edu.ar/id/eprint/3244

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