Magaudda, Adriana ORCID: https://orcid.org/0000-0001-9862-8493, Dalla Bernardina, Bernardo ORCID: https://orcid.org/0000-0002-8740-4686, De Marco, Paolo ORCID: https://orcid.org/0000-0002-9322-6986, Sfaello, Zenon Milciades, Longo, Michele ORCID: https://orcid.org/0000-0002-9188-2680, Colamaria, V., Daniele, O., Tortorella, G., Tata, M.A., Di Pierri, R. and Meduri, M. (1993) Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome. Journal of Neurology. Neurosurgery and Psychiatry, 56 (8). pp. 885-889. ISSN 0022-3050
PDF
- Versión aceptada
Disponible bajo Licencia CC Atribución-NoComercial-SinDerivadas 4.0 Internacional. Descargar (1MB) |
Resumen
Twenty patients affected by bilateral occipital cortical-subcortical calcification (BOC) are described, 19 (95%) had epilepsy. In 8 of 16 cases studied, intestinal biopsy revealed coeliac disease. Fourteen patients had occipital partial epilepsy with a relatively benign outcome, while 4 patients were affected by a severe form of epilepsy, with very frequent, drug-resistant, generalised and partial seizures with mental deterioration. One patient had a single episode of convulsive status epilepticus at four months of age. The neurological examination was normal in all patients. CT showed flocculo-nodular, cortico-subcortical BOC, without enhancement and without lobar or hemispheric atrophy. MRI was normal. The clinical and neuroimaging features of these patients are different therefore from those with the Sturge-Weber Syndrome. The study confirms a high prevalence of coliac disease in patients with BOC, but the relationship between these two pathologies still needs to be clarified.
Tipo de documento: | Artículo |
---|---|
Palabras clave: | Adolescent. Adult. Brain Diseases. Calcinosis. Celiac Disease. Child. Epilepsies. Partial. Epilepsy Generalized. Female. Human. Laterality. Male. Occipital Lobe. Syndrome. Tomography. X-Ray Computed. |
Temas: | R Medicina > R Medicina (General) |
Unidad académica: | Universidad Católica de Córdoba > Facultad de Ciencias de la Salud |
Google Académico: | Ver citaciones |
URI: | http://pa.bibdigital.ucc.edu.ar/id/eprint/3711 |
Editar ítem |