Solid-state characterization of two polymorphic forms of R-albuterol sulfate

Palacios, M.A., Cuffini, S., Badini, R., Karlsson, A. and Palacios, S.M. (2007) Solid-state characterization of two polymorphic forms of R-albuterol sulfate. Journal of Pharmaceutical and Biomedical Analysis, 43 (4). pp. 1531-1534. ISSN 0731-7085

PDF - Otro Disponible bajo Licencia CC Atribución-NoComercial-SinDerivadas 4.0 Internacional. Descargar (60kB)

Resumen

R-Albuterol (levalbuterol) is a drug used for asthma therapy and some formulations of it are in solid dosage forms. The aim of this work was to describe and characterize two polymorphic modifications of R-albuterol sulfate by means of typical structure-sensitive analytical techniques such as X-ray powder diffraction, FT-IR spectroscopy, visual and microscopic inspection, and DSC. Substantial differences were observed between the solid-state properties of the crystals, confirming the existence of at least two polymorphic forms for R-albuterol sulfate: Form I and Form II.

Tipo de documento:	Artículo
DOI:	https://doi.org/10.1016/j.jpba.2006.11.009
Palabras clave:	Crystal forms. IR. Levalbuterol sulfate. Polymorphism. R-Albuterol. XRPD.
Temas:	R Medicina > R Medicina (General)
Unidad académica:	Universidad Católica de Córdoba > Facultad de Ciencias Químicas
Google Académico:	Ver citaciones
URI:	http://pa.bibdigital.ucc.edu.ar/id/eprint/4033

Editar ítem