Producción Académica UCC

Solid-state characterization of two polymorphic forms of R-albuterol sulfate

Palacios, M.A., Cuffini, S., Badini, R., Karlsson, A. and Palacios, S.M. (2007) Solid-state characterization of two polymorphic forms of R-albuterol sulfate. Journal of Pharmaceutical and Biomedical Analysis, 43 (4). pp. 1531-1534. ISSN 0731-7085

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R-Albuterol (levalbuterol) is a drug used for asthma therapy and some formulations of it are in solid dosage forms. The aim of this work was to describe and characterize two polymorphic modifications of R-albuterol sulfate by means of typical structure-sensitive analytical techniques such as X-ray powder diffraction, FT-IR spectroscopy, visual and microscopic inspection, and DSC. Substantial differences were observed between the solid-state properties of the crystals, confirming the existence of at least two polymorphic forms for R-albuterol sulfate: Form I and Form II.

Tipo de documento: Artículo
Palabras clave: Crystal forms. IR. Levalbuterol sulfate. Polymorphism. R-Albuterol. XRPD.
Temas: R Medicina > R Medicina (General)
Unidad académica: Universidad Católica de Córdoba > Facultad de Ciencias Químicas
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