Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients

Chiurchiu, Carlos, de Alvarellos, T., Sánchez, A., Cortiñas, D., Douthat, Walter Guillermo ORCID: https://orcid.org/0000-0002-4644-6003, De La Fuente, Jorge, De Arteaga, Javier and Massari, Pablo U. (2010) Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients. Transplantation Proceedings, 42 (1). pp. 282-283. ISSN 00411345

PDF Disponible bajo Licencia CC Atribución-NoComercial-SinDerivadas 4.0 Internacional. Descargar (52kB)

Resumen

Factor V Leiden and mutation of prothrombin gene G20210A have been associated with poor results in the early post-kidney transplantation period. Its long-term importance in stable patients has yet to be evaluated. We studied the prevalence of these inherited mutations and their relationship to thrombotic events in 82 Argentine renal transplant recipients with adequate long-term kidney function. In aggregate, 7.2% of patients were carriers of these mutations; however, their presence did not show any association with thrombotic events or renal function alterations. The routine evaluation for these mutations does not seem to be cost-effective in renal transplant patients.

Tipo de documento:	Artículo
DOI:	https://doi.org/10.1016/j.transproceed.2009.11.033
Palabras clave:	Adolescent. Adult. Carrier State. Child. Creatinine. DNA Primers. Factor V. Female. Graft Rejection. Graft Survival. Humans. Kidney Transplantation. Male. Middle Aged. Mutation. Prothrombin. Thrombosis.
Temas:	R Medicina > R Medicina (General)
Unidad académica:	Universidad Católica de Córdoba > Facultad de Ciencia Política y Relaciones Internacionales
Google Académico:	Ver citaciones
URI:	http://pa.bibdigital.ucc.edu.ar/id/eprint/5010

Editar ítem